摘要 |
<p>This invention relates to a process of the preparation of the novel intermediate (S)-4-fluoromethyl-dihydro-furan-2-one of the formula (I) and with its use for the manufacture of pyrido[2,1-a] isoquinoline derivatives of the formula (II) which are useful for the treatment and / or prophylaxis of diseases which are associated with DPP IV.</p> |