发明名称 PREPARATION OF (S)-4-FLUOROMETHYL-DIHYDRO-FURAN-2-ONE.
摘要 <p>This invention relates to a process of the preparation of the novel intermediate (S)-4-fluoromethyl-dihydro-furan-2-one of the formula (I) and with its use for the manufacture of pyrido[2,1-a] isoquinoline derivatives of the formula (II) which are useful for the treatment and / or prophylaxis of diseases which are associated with DPP IV.</p>
申请公布号 MX2007014494(A) 申请公布日期 2008.02.11
申请号 MX20070014494 申请日期 2006.05.15
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 JOSEPH FORICHER;BRUNO LOHRI;STEFAN ABRECHT.;ULRICH ZUTTER;RUDOLF SCHMID;PATRIZIO MATTEI;GERARD MOINET;JEAN-MICHEL ADAM;ALEC FETTES
分类号 C07D307/32;C07D307/38 主分类号 C07D307/32
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