发明名称 |
Substance Specific to Human Pd-1 |
摘要 |
The present invention relates to a substance specific to human PD-1 comprising a part that recognizes human PD-1, a part that recognizes a membrane protein in cell membrane of human PD-1-expressing cells, and linkers. Since the substance specific to human PD-1 selectively can recognize human PD-1 and a membrane protein on cell membrane of human PD-1-expressing cells and can transmit inhibitory signal of human PD-1, it is useful for therapy and/or prevention of diseases caused by immunopathy.
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申请公布号 |
US2008025979(A1) |
申请公布日期 |
2008.01.31 |
申请号 |
US20040543323 |
申请日期 |
2004.01.22 |
申请人 |
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发明人 |
HONJO TASUKU;SHIBAYAMA SHIRO;TAKEDA KAZUHIKO;MATSUO MASAYOSHI;YOSHIDA TAKAO;MIYAMOTO MASAKAZU |
分类号 |
A61K39/395;A61P25/00;A61P31/00;A61P35/00;A61P37/00;A61P37/06;C07K16/28;C12N15/13;C12N15/63;C12P21/00;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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