发明名称 |
2-PYRIDINYL-6,7,8,9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE AND 7-PYRIDINYL-2,3-DIHYDROIMIDAZO[1,2-a] PYRIMIDIN-5(1H)ONE DERIVATIVES |
摘要 |
The invention relates to therapeutic uses of a pyrimidone derivative represented by formula (I) or a salt thereof: Wherein X, Y, R1, R2, m and n are as defined herein. Specifically, a medicament comprising the said derivative or a salt thereof as an active ingredient is used for preventive and/or therapeutic treatment of a neurodegenerative diseases caused by abnormal activity of GSK3beta such as Alzheimer's disease. |
申请公布号 |
US2008027078(A1) |
申请公布日期 |
2008.01.31 |
申请号 |
US20070841285 |
申请日期 |
2007.08.20 |
申请人 |
SANOFI-AVENTIS;MITSUBISHI PHARMA CORPORATION |
发明人 |
ALMARIO GARCIA ANTONIO;GALLET THIERRY;LI ADRIEN TAK;LOCHEAD ALISTAIR;MARGUERIE SEVERINE;NEDELEC ALAIN;SAADY MOURAD;YAICHE PHILIPPE |
分类号 |
A61K31/519;A61P3/04;A61P25/00;A61P25/28 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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