HYBRID PROTEIN FORMING HETERO DIMER

摘要

PROBLEM TO BE SOLVED: To provide a method for producing a hybrid protein, and a pharmaceutical composition consisting of the hybrid protein.

SOLUTION: This hybrid protein contains 2 co-expression amino acid sequences for forming a dimer. Each of the sequences contains a linking portion of a receptor such as TBP1 or TBP2, or a ligand such as IL-6, IFN-β and TPO linked with a hetero dimeric proteinous hormone subunit such as hCG. Each of co-expressing sequences contains a hormone subunit corresponding to the formation of the hetero dimer on its expression. The corresponding DNA molecule, expression vector and host cell, and a method for producing the protein and the pharmaceutical composition are also provided.

COPYRIGHT: (C)2008,JPO&INPIT