发明名称 METHOD FOR TREATING OCULAR CANCER
摘要 <p>It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53 activator. In particular embodiments, the p53 activator blocks the interaction between DM2 or DMX and p53. As the p53 activator induces ocular cancer cell death, a method for preventing or treating ocular cancer is also provided.</p>
申请公布号 WO2008014216(A1) 申请公布日期 2008.01.31
申请号 WO2007US74149 申请日期 2007.07.24
申请人 ST. JUDE CHILDREN'S RESEARCH HOSPITAL;FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY, VIB VZW;LEIDEN UNIVERSITY MEDICAL CENTER;DYER, MICHAEL, A.;MARINE, JEAN-CHRISTOPHE;JOCHEMSEN, AART, GERRIT 发明人 DYER, MICHAEL, A.;MARINE, JEAN-CHRISTOPHE;JOCHEMSEN, AART, GERRIT
分类号 A61K49/00;G01N33/48 主分类号 A61K49/00
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