发明名称 PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL FORM I
摘要 <p>The present invention provides an improved process for the manufacture of candesartan cilexetil form I. Further disclosed is a candesartan cilexetil preparation containing less than 0.15%, preferably less than 0.10%, of (+-)-1 -Hydroxyethyl candesartan oxanyl carbonate (ester) of the following formula (V) wherein one of A, B and C is an oxygen atom and the other two are -CH&lt;SUB&gt;2&lt;/SUB&gt;- groups.</p>
申请公布号 WO2008012372(A1) 申请公布日期 2008.01.31
申请号 WO2007EP57804 申请日期 2007.07.27
申请人 KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO;ZUPANCIC, SILVO;BENKIC, PRIMOZ;SMRKOLJ, POLONA;SENICAR, SUZANA;SOSTARIC-VIRC, NIVES;HVALA, JERNEJ 发明人 ZUPANCIC, SILVO;BENKIC, PRIMOZ;SMRKOLJ, POLONA;SENICAR, SUZANA;SOSTARIC-VIRC, NIVES;HVALA, JERNEJ
分类号 C07D309/12;A61K31/4184;A61P9/00;C07C22/00;C07D403/10;C07D407/14 主分类号 C07D309/12
代理机构 代理人
主权项
地址