发明名称 |
HEYL AS A THERAPEUTIC TARGET AND A DIAGNOSTIC MARKER FOR NEOPLASIA AND USES THEREFOR |
摘要 |
The invention generally features compositions and methods that are useful for treating or diagnosing a neoplasia, in particular breast neoplasia. The invention is based in part on the observation that the basic helix loop helix transcription factor HEYL was found to be overexpressed in breast cancer cells. Accordingly, the invention provides therapeutic compositions and methods for altering the levels and expression of HEYL of the invention, thereby treating a neoplasia, as well as compositions and methods for diagnosing a neoplasia. |
申请公布号 |
WO2007136856(A3) |
申请公布日期 |
2008.01.31 |
申请号 |
WO2007US12182 |
申请日期 |
2007.05.21 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY;SUKUMAR, SARASWATI;HAN, LIANGFENG |
发明人 |
SUKUMAR, SARASWATI;HAN, LIANGFENG |
分类号 |
C07K16/00;C12P21/08 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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