发明名称 CANCEROUS DISEASE MODIFYING ANTIBODIES
摘要 <p>The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segreg ating the anti-cancer antibodies using cancer cell cytotoxicity as an end po int, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of s taging and diagnosis of a cancer, and can be used to treat primary tumors an d tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p>
申请公布号 CA2666515(A1) 申请公布日期 2008.01.31
申请号 CA20072666515 申请日期 2007.07.24
申请人 F.HOFFMANN-LA ROCHE AG 发明人 HAHN, SUSAN E.;DACRUZ, LUIS A. G.
分类号 C07K16/28;A61K39/395;A61K51/10;A61P35/00;C07K16/18;C07K16/46;C12P21/08;G01N33/574;G01N33/577 主分类号 C07K16/28
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