| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an AT1-receptor antagonist for preventing and treating postischemic renal failure and for protecting ischemic kidneys. <P>SOLUTION: The invention relates to the compound, (S)-N-(1-carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)biphenyl-4-yl-methyl]amine (valsartan), of formula (a) or a salt thereof, in particular a pharmaceutically acceptable salt thereof, which can be used for treating acute and chronic postischemic renal failure and for protecting the ischemic kidney. <P>COPYRIGHT: (C)2008,JPO&INPIT</p> |
