| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a substituted morpholine compound for treating central nervous system disorders. <P>SOLUTION: The compound expressed by formula (I) or its pharmaceutically permissible salts are provided. In the formula, A expresses O or S; X expresses a heterocyclic ring; R<SP>1</SP>to R<SP>5</SP>express each H, a 1-6C alkyl, an aryl, a 3-8C cycloalkyl, a 1-6C alkenyl, a 5-8C cycloalkenyl, a (CH<SB>2</SB>)<SB>n</SB>-3-8C cycloalkyl, a 1-6C alkoxy, an O-aryl or the like; * expresses a first chiral center; Ð expresses a second chiral center. <P>COPYRIGHT: (C)2008,JPO&INPIT</p> |
