发明名称 |
Model Taste Cells and Methods of Use for Identifying Modulators of Taste Sensation |
摘要 |
The present invention provides model taste cells that naturally or recombinantly express taste receptors and relevant cellular proteins and/or molecules useful for taste signal transduction. The present invention further provides methods of use for these model taste cells for screening for compounds that modulate sweet and/or other taste signal transduction. Compositions comprising the compounds/modulators identified using the model taste cells are also provided. In preferred embodiments, the model taste cells are derived from human HuTu-80 enteroendocrine cells, and derivative cells thereof.
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申请公布号 |
US2008026416(A1) |
申请公布日期 |
2008.01.31 |
申请号 |
US20070829468 |
申请日期 |
2007.07.27 |
申请人 |
RADHAKRISHNA HARISH;BROWN MICHAEL D |
发明人 |
RADHAKRISHNA HARISH;BROWN MICHAEL D. |
分类号 |
C12Q1/02;C12N5/08;C12Q1/34;C12Q1/48 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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