发明名称 |
Compositions and methods for regulating bacterial pathogenesis |
摘要 |
The production of a purified extracellular bacterial signal called autoinducer-2 is regulated by changes in environmental conditions associated with a shift from a free-living existence to a colonizing or pathogenic existence in a host organism. Autoinducer-2 stimulates LuxQ luminescence genes, and is believed also to stimulate a variety of pathogenesis related genes in the bacterial species that produce it. A new class of bacterial genes is involved in the biosynthesis of autoinducer-2.
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申请公布号 |
US7323340(B2) |
申请公布日期 |
2008.01.29 |
申请号 |
US20030409783 |
申请日期 |
2003.04.07 |
申请人 |
UNIVERSITY TECHNOLOGIES INTERNATIONAL;PRINCETON UNIVERSITY |
发明人 |
BASSLER BONNIE L.;SURETTE MICHAEL G. |
分类号 |
C12N1/21;A61K31/00;A61K38/00;C07K14/195;C12N15/74;C12Q1/18;C12Q1/68 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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