发明名称 Use of methylene blue and related compounds to prevent or reverse an exaggerated hemodynamic reaction
摘要 The present invention relates to the use of the dye methylene blue (MB) or a related compound to prevent or reverse an exaggerated hemodynamic reaction in animals in need thereof, including humans. More specifically, the present invention concerns the use of MB or a related compound to prevent or reverse hypotension, unstable angina, myocardial infarction or shock caused by the concomitant ingestion of a phosphodiesterase inhibitor, such as sildenafil citrate, and a NO-donor, such as L-arginine, or an organic nitrate, such as nitroglycerin.
申请公布号 US7323461(B2) 申请公布日期 2008.01.29
申请号 US20030401819 申请日期 2003.03.28
申请人 MONTREAL HEART INSTITUTE 发明人 JUNEAU MARTIN;TANGUAY JEAN-FRANCOIS;BROUILLETTE DENIS
分类号 A61K31/5415;A61K31/00;A61K31/519;A61K45/06;A61P9/02;A61P39/02 主分类号 A61K31/5415
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