发明名称 |
Assays for identification of topoisomerase inhibitors |
摘要 |
The instant invention provides a continuous spectroscopic assay for DNA topoisomerase activity. The invention further provides topoisomerase inhibitors and pharmaceutical compositions for the treatment of topoisomerase associated diseases and disorders.
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申请公布号 |
US2008020973(A1) |
申请公布日期 |
2008.01.24 |
申请号 |
US20070701981 |
申请日期 |
2007.02.01 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
STIVERS JAMES T.;KWON KEEHWAN |
分类号 |
A61K31/05;A61K31/04;A61K31/045;A61K31/08;A61K31/095;A61K31/10;A61K31/19;A61K31/195;A61K31/28;A61K31/285;A61K31/29;A61K31/34;A61K31/35;A61K31/36;A61K31/40;A61K31/405;A61K31/44;A61K31/47;A61K31/497;A61K31/505;A61K31/535;A61K31/555;A61K31/56;A61K38/00;A61P43/00;C12Q1/68;G01N33/53 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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地址 |
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