发明名称 |
Antigen mimotopes and vaccine against cancerous diseases |
摘要 |
The present invention relates to a vaccine against cancerous diseases and antigen mimotopes associated with the high molecular weight melanoma associated antigen (HMW-MAA). The vaccines and antigen mimotopes are recognized immunologically by the monoclonal HMW-MAA antibody 225.28S and comprise at least one peptide with a length of 6 to 14 amino acids. The inventive vaccine permits active immunization against cancerous diseases associated with the high molecular weight melanoma associated antigen (HMW-MAA), whereby both prophylactic and therapeutic effects can be achieved. Further, the antigen mimotopes can serve to detect the immune response obtained.
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申请公布号 |
US2008019992(A1) |
申请公布日期 |
2008.01.24 |
申请号 |
US20070710472 |
申请日期 |
2007.02.26 |
申请人 |
ZIELINSKI CHRISTOPH;SCHEINER OTTO;JENSEN-JAROLIM ERIKA;BREITENEDER HEIMO;PEHAMBERGER HUBERT |
发明人 |
ZIELINSKI CHRISTOPH;SCHEINER OTTO;JENSEN-JAROLIM ERIKA;BREITENEDER HEIMO;PEHAMBERGER HUBERT |
分类号 |
A61K39/00;A61P35/00;C07K7/06;C07K7/08 |
主分类号 |
A61K39/00 |
代理机构 |
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