| 发明名称 |
(S)-(-)-1-(4-Fluoroisoquinolin-5-Yl)Sulfonyl-2-Methyl-1,4-Homopiperazine Hydrochloride Dihydrate |
| 摘要 |
The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.
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| 申请公布号 |
US2008021018(A1) |
申请公布日期 |
2008.01.24 |
| 申请号 |
US20050720288 |
申请日期 |
2005.11.29 |
| 申请人 |
KOWA CO., LTD;D. WESTERN THERAPEUTICS INSTITUTE, INC. |
发明人 |
OHSHIMA TAKESHI;HIDAKA HIROYOSHI;SHIRATSUCHI MASAMI;ONOGI KAZUHIRO;ODA TOSHIAKI |
| 分类号 |
A61K31/551;A61P9/00;C07D243/08 |
主分类号 |
A61K31/551 |
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