发明名称 |
COMPOSITIONS AND METHODS FOR DETECTION OF SIROLIMUS |
摘要 |
<p>Compounds are disclosed comprising a moiety, such as a poly(amino acid), a non-poly(amino acid) label moiety, or a non-poly(amino acid) immunogenic carrier, linked to a sirolimus compound at position 26 or at position 32. Such sirolimus compounds comprising an immunogenic carrier can be employed to raise both polyclonal and monoclonal antibodies to the sirolimus compound. Polyclonal antibodies are also disclosed, which are raised against a compound wherein a moiety, such as a poly(amino acid), a non-poly(amino acid) label moiety, or a non-poly(amino acid) immunogenic carrier, is linked to a sirolimus compound at position 32. The above antibodies and sirolimus compounds comprising a label can be used in assays for the detection of sirolimus compounds.</p> |
申请公布号 |
EP1880215(A2) |
申请公布日期 |
2008.01.23 |
申请号 |
EP20060758774 |
申请日期 |
2006.04.27 |
申请人 |
DADE BEHRING INC. |
发明人 |
WORLEY, CATHY, K.;YANG, YALI;ZHENG, YI-FENG;LIU, HSHIOU-TING;KEIM, HOLGER;CHEN, JIAN |
分类号 |
G01N33/532;C07D267/00;C07K1/13;C07K16/44;G01N33/94 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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