Liquid formulation comprising clozapine, quetiapine, a salt of quetiapine and/or olanzapine for oral administration

摘要

Use of composition comprising clozapine (20-100 mg/ml), quetiapine (25-100 mg/ml), one or more hardly soluble acid addition salt of quetiapine (quetiapine base) (25-100 mg/ml) and/or olanzapine (1-10 mg/ml); benzyl alcohol and/or phenylethyl alcohol (0-20 mg/ml); propylene glycol (25-150 mg/ml) and up to 50 mg/ml of ethanol and/or up to 0.5 wt.% of one or more 3-4C-alkanol; one or more ethereal oil (0-50 mg/ml), flavor and/or sweetener; and one or more liquid polyethylene glycol (residue up to 1 ml), to prepare a solution for oral administration, is claimed. ACTIVITY : Neuroleptic. MECHANISM OF ACTION : None given.