发明名称 |
METHOD FOR PURIFYING PREPROINSULIN |
摘要 |
The invention relates to a method for the chromatographic purification of preproinsulins, in which higher molecular weight substances are removed from an aqueous solution of preproinsulin by a first chromatography on an anion exchanger in flow-through mode and a subsequent second chromatography on a cation exchanger in adsorption mode, and to a method for preparing insulins, which includes the method for preparing preproinsulins. |
申请公布号 |
EP1527097(B1) |
申请公布日期 |
2008.01.23 |
申请号 |
EP20030766211 |
申请日期 |
2003.07.18 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
THUROW, HORST;BLUMENSTOCK, HANS;HAVENITH, CHANTALLE |
分类号 |
C07K14/62 |
主分类号 |
C07K14/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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