发明名称 |
OLIGONUCLEOTIDES OR THEIR FUNCTIONAL HOMOLOGUES, A COMPOSITION COMPRISING THE SAME AND A METHOD OF TREATING B CELL NEOPLASM |
摘要 |
The invention provides nine oligonuleotides with sequences of SEQ ID NO: 1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonuleotides or their functional homologues or the composition comprising the oligonuleotides. The oligonuleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells. |
申请公布号 |
KR20080007655(A) |
申请公布日期 |
2008.01.22 |
申请号 |
KR20077028065 |
申请日期 |
2006.02.13 |
申请人 |
CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD. |
发明人 |
WANG LI YING;BAO MU SHENG;YU YONG LI |
分类号 |
C12N15/00;A61K31/7088;C07H21/04;C12N15/117 |
主分类号 |
C12N15/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|