КРИСТАЛЛИЧЕСКАЯ ФОРМА МОНОЦИТРАТА 3-{(3R,4R)-4-МЕТИЛ-3-[МЕТИЛ-(7Н-ПИРРОЛО[2,3-d] ПИРИМИДИН-4-ИЛ)АМИНО]ПИПЕРИДИН-1-ИЛ}-3-ОКСО-ПРОПИОНИТРИЛА И ЕЕ ПРИМЕНЕНИЕ

摘要

This invention relates to novel amorphous and crystallline forms of 3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3 -oxo-propionitrile mono citrate salt, useful as inhibitors of protein kinases, and to their methods of preparation.