发明名称 SPECIFIC ALKYLENE DIAMINE-SUBSTITUTED HETEROCYCLE
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a novel NPY receptor, particularly a non-peptidic antagonist of an NPY<SB>1</SB>receptor. <P>SOLUTION: A compound being substituted with a specific alkylenediamine and having a specific modified mono-, bi-, or tricyclic heterocyclic core is used. The compound is a receptor, inhibits the activity of neuropeptide Y, and is useful for treating physiological disorders associated with an excess of neuropeptide Y, including eating disorders, such as, for example, obesity and bulimia, and certain cardiovascular diseases, for example, hypertension. <P>COPYRIGHT: (C)2008,JPO&INPIT</p>
申请公布号 JP2008007515(A) 申请公布日期 2008.01.17
申请号 JP20070215782 申请日期 2007.08.22
申请人 NEUROGEN CORP;PFIZER INC 发明人 HORVATH RAYMOND F;TRAN JENNIFER;DE LOMBAERT STEPHANE;HODGETTS KEVIN JULIAN;CARPINO PHILIP A;GRIFFITH DAVID A
分类号 C07D213/74;A61K31/437;A61K31/4375;A61K31/44;A61K31/4409;A61K31/4706;A61K31/505;A61K31/519;A61K31/522;A61K45/00;A61P1/12;A61P3/04;A61P3/06;A61P3/10;A61P5/00;A61P5/06;A61P5/48;A61P7/04;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/02;A61P11/06;A61P11/08;A61P13/02;A61P13/12;A61P15/00;A61P15/10;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P43/00;C07D213/73;C07D215/46;C07D239/48;C07D471/04;C07D471/14;C07D473/34;C07D475/06;C07D475/08;C07D487/04;C07D495/04 主分类号 C07D213/74
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