摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a novel NPY receptor, particularly a non-peptidic antagonist of an NPY<SB>1</SB>receptor. <P>SOLUTION: A compound being substituted with a specific alkylenediamine and having a specific modified mono-, bi-, or tricyclic heterocyclic core is used. The compound is a receptor, inhibits the activity of neuropeptide Y, and is useful for treating physiological disorders associated with an excess of neuropeptide Y, including eating disorders, such as, for example, obesity and bulimia, and certain cardiovascular diseases, for example, hypertension. <P>COPYRIGHT: (C)2008,JPO&INPIT</p> |