| 摘要 |
<p>The biaryl benzoimidazole derivative of the present invention has an exce llent inhibitory effect on calcium influx in HEK cells, thereby showing a po werful antagonistic effect on a vanilloid receptor, and further has an excel lent analgesic effect, thereby being useful for preventing or treating pain, acute pain, chronic pain, neuropathic pain, postoperative pain, migraine, a rthralgia, neuropathies, nerve injury, diabetic neuropathy, neurological ill ness, neurodermatitis, stroke, bladder hypersensitivity, irritable bowel syn drome, a respiratory disorder such as cough, asthma, and chronic obstructive pulmonary disease, burning, psoriasis, itching, vomiting, irritation of the skin, eyes, and mucous membranes, gastric-duodenal ulcers, inflammatory int estinal diseases, and inflammatory diseases.</p> |
