METHODS FOR ENHANCING PRODUCTION OF ISOPRENOID COMPOUNDS BY HOST CELLS
摘要
<p>The present invention provides methods of producing an isoprenoid or an isoprenoid precursor in a host cell that comprises a biosynthetic pathway that converts a substrate to isopentenyl pyrophosphate, where the biosynthetic pathway is modified to include a synthetic intergenic region (IGR) between at least two coding regions encoding enzymes in the biosynthetic pathway. The present invention further provides recombinant nucleic acid constructs comprising a synthetic IGR, and genetically modified host cells comprising a synthetic IGR.</p>
申请公布号
WO2008008256(A2)
申请公布日期
2008.01.17
申请号
WO2007US15498
申请日期
2007.07.03
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;KEASLING, JAY, D.;PITERA, DOUGLAS, J.;PADDON, CHRIS, J.;PFLEGER, BRIAN
发明人
KEASLING, JAY, D.;PITERA, DOUGLAS, J.;PADDON, CHRIS, J.;PFLEGER, BRIAN