Compounds of formula (I) especially where R<SUP>1</SUP> is an optionally substituted alkyl, aralkyl or heterocyclyl-alkyl group, are shown to have activity as sodium channel blockers or as antifolates. Some novel compounds where R<SUP>1</SUP> is an aralkyl or heterocyclyl-alkyl are disclosed.
申请公布号
WO2008007149(A2)
申请公布日期
2008.01.17
申请号
WO2007GB50405
申请日期
2007.07.13
申请人
UNIVERSITY OF GREENWICH;LEACH, MICHAEL;HARBIGE, LAURENCE;RIDDALL, DIETER;BARRACLOUGH, PAUL
发明人
LEACH, MICHAEL;HARBIGE, LAURENCE;RIDDALL, DIETER;BARRACLOUGH, PAUL