发明名称 |
METHODS FOR INHIBITING OSTEOCLASTOGENESIS |
摘要 |
Methods for the treatment of osteolytic bone disease and for the inhibition of osteoclastogenesis are disclosed. The methods utilize COX-2 inhibitors and/or inhibitors of NF-kB activation, administered to patients in an amount effective to inhibit osteoclastogenesis. Also disclosed are methods to modulate the expression of MIP-Ia in a subject. |
申请公布号 |
WO2007084853(A3) |
申请公布日期 |
2008.01.17 |
申请号 |
WO2007US60485 |
申请日期 |
2007.01.12 |
申请人 |
UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;LENTZSCH, SUZANNE |
发明人 |
LENTZSCH, SUZANNE |
分类号 |
A61K31/196;A61K31/365;A61K31/407;A61K31/415;A61K31/42;A61P19/08;A61P19/10;A61P21/00;A61P35/00 |
主分类号 |
A61K31/196 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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