摘要 |
<P>PROBLEM TO BE SOLVED: To provide a medicament containing at least one double-stranded oligoribonucleotide (dsRNA) designed to inhibit the expression of a target gene. <P>SOLUTION: One strand of the dsRNA is at least in part complementary to the target gene. The target gene can be selected from the following group: a cancer gene, a cytokine gene, an Id protein gene, a developmental gene, and a prion gene. The target gene can be expressed in a pathogenic organism (especially plasmodium). The target gene can also be a part of a virus or a viroid preferably pathogenic to human beings. <P>COPYRIGHT: (C)2008,JPO&INPIT |