发明名称 |
INHIBITING TUMOUR CELL INVASION, METASTASIS AND ANGIOGENESIS THROUGH TARGETTING LEGUMAIN |
摘要 |
The present invention relates to new compositions and methods useful for preventing, treating and diagnosing metastatic and/or invasive cancer and undesirable angiogenesis. For example, the invention relates to inhibitors of proteases that are specifically expressed in tumors, prodrugs activated in the tumor microenvironment and methods for using those inhibitors and prodrugs to inhibit angiogenesis and tumor cell invasion. |
申请公布号 |
WO2007064759(A3) |
申请公布日期 |
2008.01.17 |
申请号 |
WO2006US45788 |
申请日期 |
2006.11.29 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE;LIU, CHENG |
发明人 |
LIU, CHENG |
分类号 |
C07K7/02;A61K31/337;A61K38/04;C07K5/06;C07K5/08;C07K5/10;C07K9/00;G01N33/574 |
主分类号 |
C07K7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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