发明名称 |
NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS |
摘要 |
Novel substituted 4-aminopiperidine derivatives of the formula I: wherein n, R<SUP>1</SUP>, Y, (A), and (B) are as defined in claim 1 and optically pure enantiomers, mixtures of enantiomers, racemates, diastereomers, mixtures of diastereomers, diastereomeric racemates, mixtures of diastereomeric racemates and meso-forms, as well as salts and solvent complexes of such compounds, and morphological forms, that exhibit useful parasite aspartic proteases inhibiting properties and can thus be used in the form of pharmaceutical compositions as antimalarial medicines. |
申请公布号 |
WO2006056930(A3) |
申请公布日期 |
2008.01.17 |
申请号 |
WO2005IB53838 |
申请日期 |
2005.11.21 |
申请人 |
ACTELION PHARMACEUTICALS LTD;BOSS, CHRISTOPH;CORMINBOEUF, OLIVIER;GRISOSTOMI, CORINNA;WELLER, THOMAS;BUR, DANIEL;PRADE, LARS |
发明人 |
BOSS, CHRISTOPH;CORMINBOEUF, OLIVIER;GRISOSTOMI, CORINNA;WELLER, THOMAS;BUR, DANIEL;PRADE, LARS |
分类号 |
C07D211/58;A61K31/4409;A61P33/06;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/12;C07D413/14 |
主分类号 |
C07D211/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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