发明名称 USE OF AMPK-ACTIVATING IMIDAZOLE DERIVATIVES, PREPARATION PROCESS THEREFOR AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
摘要 The invention relates to the use of imidazole derivatives of the formula (I): in which A, R'1, R'2 and R'3 are as defined in the description, as AMPK activators. The invention also relates to processes for the preparation of the said compounds, to their uses for the preparation of medicaments for the treatment of insulin resistance, diabetes and related pathologies, and also obesity, and to the pharmaceutical compositions comprising them. Certain co mpounds of the formula (I) are novel and, in this respect, also form part of the invention.
申请公布号 CA2657335(A1) 申请公布日期 2008.01.17
申请号 CA20072657335 申请日期 2007.06.12
申请人 MERCK PATENT GMBH 发明人 HALLAKOU-BOZEC, SOPHIE;MARAIS, DOMINIQUE;CHARON, CHRISTINE;MOINET, GERARD
分类号 A61K31/4164;A61P3/00;A61P3/10;C07D233/90 主分类号 A61K31/4164
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