SYNTHETIC AND STANDARDIZED PRION INFECTUOUS MATERIAL, AND USES THEREOF AS AN INFECTING INOCULUM

摘要

The invention concerns a novel, synthetic, standardised, soluble, reproducible and easy-to-handle infectious material of the prion type, consisting of a cell lysate or culture supernatant from stable transgenic cells expressing a prion protein PrP and supporting replication of the pathogenic form, PrPsc, of the said Prp.