发明名称 |
PHOTOCROSSLINKABLE OLIGO(POLY (ETHYLENE GLYCOL) FUMARATE) HYDROGELS FOR CELL AND DRUG DELIVERY |
摘要 |
The invention provides photocrosslinkable, injectable, biodegradable oligo(poly(ethylene glycol) fumarate) (OPF) hydrogels made from the photopolymerization of an OPF macromer with UV light and a photoinitiator. Hydrogels with varying mechanical properties and water content can be made with changes in macromer and crosslinking agent concentration in a precursor solution. The biodegradable OPF hydrogels can be injected as a fluid into a bodily defect of any shape, may incorporate various therapeutic agents, e.g., cells and/or growth factors, and may be implanted via minimally invasive arthroscopic techniques. |
申请公布号 |
EP1877000(A1) |
申请公布日期 |
2008.01.16 |
申请号 |
EP20060748605 |
申请日期 |
2006.03.23 |
申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH |
发明人 |
DADSETAN, MAHROKH;YASZEMSKI, MICHAEL;LU, LICHUN |
分类号 |
C08F283/06;A61L27/18;A61L27/38;A61L27/50;A61L27/52;A61L27/56;C08F289/00;C08F290/00;C08F290/06;C08F290/14;C08J3/24;C08J3/28;C08L51/08 |
主分类号 |
C08F283/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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