发明名称 ТЕТРОНОВАЯ КИСЛОТА И ТЕТРАМОВАЯ КИСЛОТА-ИНГИБИТОРЫ БЕТА-СЕКРЕТАЗЫ
摘要 This invention relates to new tetronic and tetramic acid derivatives with beta-secretase inhibitory activity of formula I: wherein R1, R2, R3, R4, R5, R5', R6 and R6' are as defined hereinabove, to processes for their preparation, compositions containing said tetronic and tetramic acid derivatives and their use in the treatment and prevention of diseases modulated by an inhibitor of beta-secretase, such as Alzheimer's disease.
申请公布号 RU2006122851(A) 申请公布日期 2008.01.10
申请号 RU20060122851 申请日期 2004.11.22
申请人 Ф.ХОФФМАНН-ЛЯ РОШ АГ (CH) 发明人 ГОДЕЛЬ Тьерри (CH);ХИЛЬПЕРТ Ханс (CH);ХУММ Роланд (DE);РОДЖЕРС-ЭВАНС Марк (CH);РОМБАШ Дидье (FR);ШТАЛЬ Кристоф Мартин (DE);ВАЙСС Петер (CH);ВОШТЛЬ Вольфганг (DE)
分类号 C07D307/60;C07D207/38;C07D401/06;C07D403/06;C07D405/06;C07D409/06;C07D417/06;C07D495/06 主分类号 C07D307/60
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