NOVEL GENES AND MARKERS IN ESSENTIAL ARTERIAL HYPERTENSION
摘要
<p>The present invention relates to previously unknown disease associations between various genes, loci and biomarkers and essential hypertension. The detection of these biomarkers provides novel in vitro methods and test kits which can be used as an aid when making risk assessment, molecular diagnosis or prognosis of HT or a HT related condition. The disclosed methods and test kits do not require interaction with the body of a subject during the biomarker detection. Instead the methods and test kits are for in vitro use (e.g. in a clinical laboratory) and typically biological samples for the biomarker analyses using a method or a test kit of this invention have been collected earlier in a different place. In addition the biomarkers provide methods and systems for identifying novel agents for preventing, treating and/or reducing risk of HT or a HT related condition. The HT associated genes can be used to develop novel therapies for prevention and/or treatment of essential hypertension.</p>
申请公布号
WO2008003826(A1)
申请公布日期
2008.01.10
申请号
WO2007FI50407
申请日期
2007.07.02
申请人
OY JURILAB LTD;SALONEN, JUKKA, T.;AALTO, JUHA-MATTI;UIMARI, PEKKA;PIRSKANEN, MIA
发明人
SALONEN, JUKKA, T.;AALTO, JUHA-MATTI;UIMARI, PEKKA;PIRSKANEN, MIA