发明名称 METHOD FOR PREPARING CRYSTALS, CRYSTALS AND PHARMACEUTICAL AGENT
摘要 FIELD: steroids, pharmacy. ^ SUBSTANCE: invention describes a method for preparing crystals showing the mean coarseness index in the required limits from 3 to 25 mcm and maximal size 100 mcm, not above. Method involves the crystallization process of supersaturated solution of compound representing 11beta-benzaldoximestra-4,9-diene wherein it is subjected for wetted grinding by using the correspondence device designated for such wetted grinding to obtain suspension of primary grains. Also, invention crystals prepared by the proposed method and a pharmaceutical agent containing these crystals. ^ EFFECT: improved preparing method. ^ 14 cl, 8 tbl, 4 dwg, 4 ex
申请公布号 RU2314315(C2) 申请公布日期 2008.01.10
申请号 RU20040134327 申请日期 2003.04.22
申请人 SHERING AKTSIENGEZEL'SHAFT 发明人 GRAVE DETLEF;GEREKKE KHAGEN;KHEZEL' PETER;AJKHARDT ANNETTE;GLIZING ZABINE;MJULLER UVE
分类号 C07J41/00;A61K9/14;A61K31/56;A61K31/569;A61P5/24;A61P15/00;A61P15/18;A61P17/02;A61P35/00 主分类号 C07J41/00
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