发明名称 |
Anti-endotoxic, antimicrobial cationic peptides, the encoding DNA and methods of use thereof |
摘要 |
A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
|
申请公布号 |
US2008009445(A1) |
申请公布日期 |
2008.01.10 |
申请号 |
US20070707813 |
申请日期 |
2007.02.15 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HANCOCK ROBERT E.W.;GOUGH MONISHA A.;PATRZYKAT ALEKSANDER;WOODS DONALD;JIA XIAOYAN |
分类号 |
A61K31/711;A61K38/00;A61K38/16;A61P31/04;C07K14/47 |
主分类号 |
A61K31/711 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|