发明名称 TOXIN DETECTION METHOD
摘要 Disclosed are: an antibody directed against Panton-Valentine leukocidin (PVL) toxin derived from Staphylococcus aureus; a method and a kit for the detection of the toxin using the antibody; and a pharmaceutical composition for the treatment of PVL-carrying Staphylococcus aureus, which comprises an antibody directed against Panton-Valentine leukocidin toxin. Specifically, disclosed are: an antibody capable of binding to Panton-Valentine leukocidin F and having no cross-reactivity with LukD and/or HlgB; and an antibody capable of binding to Panton-Valentine leukocidin S and having no cross-reactivity with at least one member selected from LukE, HlgC and HlgA.
申请公布号 WO2008004536(A1) 申请公布日期 2008.01.10
申请号 WO2007JP63278 申请日期 2007.07.03
申请人 JUNTENDO UNIVERSITY SCHOOL OF MEDICINE;DENKA SEIKEN CO., LTD.;OHISHI, KANENARI;BABA, TADASHI;HIRAMATSU, KEIICHI;NAKATOMI, YASUO 发明人 OHISHI, KANENARI;BABA, TADASHI;HIRAMATSU, KEIICHI;NAKATOMI, YASUO
分类号 C07K16/12;A61K39/09;A61K39/395;A61P31/04;A61P37/04;G01N33/53;G01N33/569 主分类号 C07K16/12
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