摘要 |
A method of easily measuring whether or not an LXR ligand has the function of effecting, e.g., increasing, plasma triglyceride concentration and/or LDL cholesterol concentration in a mammal by using the binding activity between LXR and a coactivator, and a method of identifying LXR ligands that do not have the function of effecting, e.g., increasing, plasma triglyceride concentration and/or LDL cholesterol concentration by using the binding activity between LXR and a coactivator. |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED.;TERASAKA, NAOKI;HONZUMI, SHOKO;SCHULMAN, IRA GLENN;WAGNER, BRANDEE LYNN;WILLY, PATRICIA J. |
发明人 |
TERASAKA, NAOKI;HONZUMI, SHOKO;SCHULMAN, IRA GLENN;WAGNER, BRANDEE LYNN;WILLY, PATRICIA J. |