| 摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to modulators of estrogen receptors of the formula (I): wherein each R1 and R2 is chosen independently from hydrogen or halogen atom; each R5, R6, R7, R8 and R9 represents independently hydrogen, halogen atom or -CN group under condition that at least one radical among R5 or R9 doesn't means hydrogen atom, or to their pharmaceutically acceptable salts. Also, invention relates to a method for synthesis of claimed compounds, a pharmaceutical composition and using compound of the formula (I) for producing a medicinal agent possessing activity of agonist or antagonist of estrogen receptor, and to methods for treatment or inhibition of different diseases. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 20 cl, 15 sch, 14 tbl, 55 ex |
