发明名称 FUSED BICYCLIC COMPOUNDS INTERACTING WITH THE HISTAMINE H4 RECEPTOR
摘要 Compounds that interact with the histamine H4 receptor, and which may be useful for treating or preventing disorders and conditions mediated by the h istamine H4 receptor, e.g. inflammation, are of formula (I) wherein Q is CR1 or N; X is CR2 or N, provided that Q and X are not both N; Y is CR3 or N; Z is CH or N; R1, R2, R3, R4, R5 and R6 are independently H, F, Cl, Br, I, or a hydrocarbon group which optionally contains one or more heteroatoms; and R7 is a heterocyclic radical including one or more N atoms; or a pharmaceuti cally acceptable salt, ester or solvate thereof.
申请公布号 CA2657702(A1) 申请公布日期 2008.01.10
申请号 CA20072657702 申请日期 2007.07.03
申请人 VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN P 发明人 LEURS, REGORIUS;SMITS, ROGIER ADRIAAN;VAN LIM, HERMAN DIRNAWAN;DE ESCH, IWAN JOZEF PHILOMENA
分类号 C07D215/38;A61K31/505;A61P29/00;A61P37/08;C07D217/22;C07D239/84;C07D239/95;C07D241/44;C07D403/04;C07D403/06;C07D451/06 主分类号 C07D215/38
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