摘要 |
Compounds that interact with the histamine H4 receptor, and which may be useful for treating or preventing disorders and conditions mediated by the h istamine H4 receptor, e.g. inflammation, are of formula (I) wherein Q is CR1 or N; X is CR2 or N, provided that Q and X are not both N; Y is CR3 or N; Z is CH or N; R1, R2, R3, R4, R5 and R6 are independently H, F, Cl, Br, I, or a hydrocarbon group which optionally contains one or more heteroatoms; and R7 is a heterocyclic radical including one or more N atoms; or a pharmaceuti cally acceptable salt, ester or solvate thereof. |
申请人 |
VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN P |
发明人 |
LEURS, REGORIUS;SMITS, ROGIER ADRIAAN;VAN LIM, HERMAN DIRNAWAN;DE ESCH, IWAN JOZEF PHILOMENA |