Activator of peroxisome proliferator-activated receptor delta

摘要

A compound represented by the following general formula (I): (wherein R¹ represents phenyl, etc. which can have substituents selected from the group consisting of C_1-8 alkyl, C_1-8 alkyl having halogen, halogen, hydroxyl, etc.; R² represents C_1-8 alkyl, etc.; A represents oxygen, sulfur, etc.; X represents C_1-8 alkylene chain, etc.; Y represents C(-O), CH-CH, etc.; R³, R⁴, and R⁵ each represents hydrogen, C_1-8 alkyl, etc.; B represents CH or nitrogen; Z represents oxygen or sulfur; R⁶ and R⁷ each represents hydrogen, C_1-8 alkyl, etc.; and R⁸ represents hydrogen or C_1-8 alkyl; provided that at least one of R³, R⁴, and R⁵ is not hydrogen) or a salt of the compound; and a PPAR-delta activator which contains the compound or salt as the active ingredient.