发明名称 THE USE OF PVP TO CONTROL THE RELEASE PROFILE OF AN ACTIVE INGREDIENT FROM A HYDROPHILIC POLYMER MATRIX TABLET
摘要 The invention relates to the use of polyvinyl pyrrolidone (PVP) for the modulation of drug release kinetics from hydrophilic polymer matrix tablets, in particular hydroxypropyl methyl cellulose (HPMC) matrix tablets. Another aspect of the invention is a method of drug release from a hydrophilic polymer matrix tablet, for example a hydroxypropyl methyl cellulose (HPMC) and compositions thereof.
申请公布号 WO2008004001(A2) 申请公布日期 2008.01.10
申请号 WO2007GB50375 申请日期 2007.07.04
申请人 MERCK SHARP & DOHME LIMITED;HARDY, IAN;FITZPATRICK, SHAUN;AJAYI, TOLULOPE;WINDBERG-BAARUP, ANNE;CHADWICK, GARETH;NERI, CLAUDIA;BYWAY, PAUL VINCENT 发明人 HARDY, IAN;FITZPATRICK, SHAUN;AJAYI, TOLULOPE;WINDBERG-BAARUP, ANNE;CHADWICK, GARETH;NERI, CLAUDIA;BYWAY, PAUL VINCENT
分类号 A61K9/22 主分类号 A61K9/22
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