METHOD AND DEVICE FOR SUBSTANCE SEPARATION USING COMPATIBLE MULTIPHASE SOLVENT SYSTEM

摘要

A method for separating a target substance from a mixture using a first solvent and a second solvent wherein the first solvent and the second solvent undergo a reversible phase change from a biphasically separated state into a mutually dissolved monophasic state by means of changing the temperature, wherein an upstream region and an intermediate region of a column containing the first solvent are kept within a range of the temperature allowing for a monophasic mutual dissolution and a downstream region of the column is kept within a range of the temperature allowing for a biphasic separation, wherein the second solvent containing the mixture dissolved therein is loaded onto the column from the upstream of the column and thereafter the second solvent phase separated in the downstream region of the column is taken out whereby separating the target substance.