发明名称 PYRIMIDYLAMINOBENZAMIDE DERIVATIVES FOR HYPEREOSINOPHILIC SYNDROME
摘要 The present invention relates to the use of pyrimidylaminobenzamide derivatives for the preparation of a drug for the treatment of FIP1L1-PDGFRE-induced or TEL-PDGFRF-induced myeloproliferative diseases, especially for the curative and/or prophylactic treatment of hypereosinophilic syndrome and hypereosinophilc syndrome with resistance to imatinib, and to a method of treating hypereosinophilic syndrome, chronic eosinophilic leukemia and hypereosinophilic syndrome with resistance to imatinib, or other diseases associated with FIP1L1-PDGFRE, TEL-PDGFRF or similar mutations that activate PDGFR.
申请公布号 KR20080004564(A) 申请公布日期 2008.01.09
申请号 KR20077025365 申请日期 2007.11.01
申请人 NOVARTIS AG 发明人 MANLEY PAUL W.;MESTAN JUERGEN;FABBRO DORIANO
分类号 C07D401/04;A61K31/506;C07D401/14 主分类号 C07D401/04
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