发明名称 |
CURCUMOL DERIVATIVES, THE COMPOSITIONS COMPRISING THE SAME AND THE USE OF THE SAME IN THE MANUFACTURE OF MEDICAMENT |
摘要 |
The present invention provides curcumol derivatives of the following formula (I) or pharmeceutical acceptable salts thereof:
wherein, Y is selected from the group consisting of =CHR 2 , -CH 2 R 2 , =O,
-OH or -OR 1 ;R 1 is selected from H, R, RCO or HO 3 S; and R is selected from the group consisting of H; saturated or unsaturated linear C 1-10 hydrocarbon group and the like; R 2 is selected from the group consisting of F; Cl; Br; I; H; -OH; -OR; -HSO 3 and the like; with the proviso that both R 1 and R 2 are not H. The present invention also provides anti-tumor or antiviral pharmaceutical compositions comprising said derivatives or pharmeceutical acceptable salts thereof. The present invention further provides the use of said derivatives or pharmeceutical acceptable salts thereof in the preparation of a medicament for prophylaxis and/or treatment tumor or an antiviral medicament. |
申请公布号 |
EP1749830(A4) |
申请公布日期 |
2008.01.09 |
申请号 |
EP20050749349 |
申请日期 |
2005.05.26 |
申请人 |
HANGZHOU MINSHENG PHARMACEUTICALS CO., LTD. |
发明人 |
WANG, SHULONG;GUO, DIANWU;MENG, ZHAOKE |
分类号 |
C07D493/08;A61K31/352;A61P31/12;A61P35/00;C07D493/10;C07D493/20 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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