| 发明名称 |
SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AS ANTI-FUNGAL AGENTS |
| 摘要 |
<p>The present invention pertains to substances of the formula (I) wherein X is O or S; and R1-R4 are defined in the claims as inhibitors of glyoxalase I and/or II, pharmaceutical compositions comprising one or more compounds according to formula (I) and the use of one or more compounds according to formula (I) for the treatment of diseases associated with increased glycolytic metabolism. In one embodiment, the disease is a bacterial infection.</p> |
| 申请公布号 |
EP1874407(A2) |
申请公布日期 |
2008.01.09 |
| 申请号 |
EP20060742586 |
申请日期 |
2006.04.13 |
| 申请人 |
BIOMAC PRIVATINSTITUT FUER MEDIZINISCHE UND ZAHNMEDIZINISCHE FORSCHUNG, ENTWICKLUNG UND DIAGNOSTIK GMBH |
发明人 |
HUSE, KLAUS;BIRKENMEIER, GERD;BIRKENMEIER, MONIKA |
| 分类号 |
A61P35/00 |
主分类号 |
A61P35/00 |
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