| 发明名称 |
Basal cell carcinoma tumor suppressor protein |
| 摘要 |
This invention provides for a tumor suppressor gene inactivation of which is a causal factor in nevoid basal cell carcinoma syndrome and various sporadic basal cell carcinomas. The NBCCS gene is a homologue of the Drosophila patched (ptc) gene.
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| 申请公布号 |
US7317086(B2) |
申请公布日期 |
2008.01.08 |
| 申请号 |
US20020302279 |
申请日期 |
2002.11.22 |
| 申请人 |
UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
DEAN MICHAEL C.;HAHN HEIDI EVE;WICKING CAROL;CHRISTIANSEN JEFFREY;ZAPHIROPOULOS PETER G.;GAILANI MAE R.;SHANLEY SUSAN M.;CHIDAMBARAM ABIRAMI;VORECHOVSKY IGOR;HOLMBERG-LINDSTROM ERIKA;UNDEN ANNE B.;GILLES SUSAN A.;NEGUS KYLIE;MCLEOD SMYTH IAN;PRESSMAN CAROL L.;LEFFELL DAVID J.;GERRARD BERNARD;GOLDSTEIN ALISA M.;WAINWRIGHT BRANDON;TOFTGARD RUNE C. M.;CHENEVIX-TRENCH GEORGIA;BALE ALLEN E. |
| 分类号 |
C07K14/47;G01N33/50;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P35/00;C07K14/705;C12N5/10;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/574 |
主分类号 |
C07K14/47 |
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