发明名称 |
Mutant glycoproteins |
摘要 |
The inventors have designed novel FSH mutants with increased glycosylation and longer half-lives for use in inducing folliculogenesis in human patients. The use of a FSH mutant preparation of the invention permits the use of lower cumulative doses of FSH to achieve the same or better clinical result.
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申请公布号 |
US7317095(B2) |
申请公布日期 |
2008.01.08 |
申请号 |
US20040493540 |
申请日期 |
2004.11.17 |
申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
BRONDYK WILLIAM H.;JIANG XULIANG;CAMPBELL ROBERT |
分类号 |
C07K14/59;C12N15/09;A61K38/00;A61K38/24;A61K47/48;A61P15/08;C07K;C12N5/00;C12N5/10;C12N15/00;C12N15/16;C12N15/63;C12P21/00;C12P21/02 |
主分类号 |
C07K14/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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