发明名称 PYRAZOLE-AMINE COMPOUNDS USEFUL AS KINASE INHIBITORS
摘要 The present invention provides pyrazole derived compounds of formula (I) useful for treating p38 kinase-associated conditions, where W, X, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, R<SUB>6 </SUB>and m are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
申请公布号 US2008004278(A1) 申请公布日期 2008.01.03
申请号 US20070832924 申请日期 2007.08.02
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 DYCKMAN ALARIC J.;DAS JAGABANDHU;LEFTHERIS KATERINA;LIU CHUNJIAN;MOQUIN ROBERT V.;WROBLESKI STEPHEN T.
分类号 C07D231/10;A61K;A61K31/415;A61K31/4152;A61K31/4155;A61K31/416;A61K31/4439;A61K31/497;A61K31/501;A61K31/506;A61K31/535;A61K31/5377;A61K31/675;A61P29/00;C07D;C07D231/04;C07D231/14;C07D231/18;C07D231/56;C07D401/04;C07D401/12;C07D403/02;C07D403/04;C07D405/12;C07D413/02;C07D413/12;C07D413/14 主分类号 C07D231/10
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