发明名称 |
MICROARRAY ANALYSIS OF LIGHT CHAIN VARIABLE GENE EXPRESSION AND METHODS OF USE |
摘要 |
Disclosed are microarrays comprising a plurality of oligonucleotide species capable of hybridizing to a polynucleotide comprising a sequence encoding at least a portion of a light chain variable region or a complement thereof. Also disclosed are methods of identifying light chain variable genes associated with a disease, methods of diagnosing a disease and methods of monitoring a disease. Methods of evaluating the ability of a therapeutic agent or a treatment to alter expression of the light chain variable gene are also provided. |
申请公布号 |
US2008003605(A1) |
申请公布日期 |
2008.01.03 |
申请号 |
US20070753263 |
申请日期 |
2007.05.24 |
申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
WEIGERT MARTIN;SCHOETTLER NATHAN;NI DONGYAO |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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